BDBM50165316 8-(2,4-Dichloro-phenylsulfanyl)-9-pent-4-ynyl-9H-purin-6-ylamine::CHEMBL365118

SMILES Nc1ncnc2n(CCCC#C)c(Sc3ccc(Cl)cc3Cl)nc12

InChI Key InChIKey=KNFKPQJGTFXNMB-UHFFFAOYSA-N

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50165316   

TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sloan-Kettering Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50165316(8-(2,4-Dichloro-phenylsulfanyl)-9-pent-4-ynyl-9H-p...)
Affinity DataIC50: >3.00E+5nMAssay Description:Displacement of Cy3B-GM from recombinant Hsp90beta (unknown origin) after 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed